News Urologia

AbstractSTUDY QUESTIONDoes experimental manipulation of fibroblast growth factor 9 (FGF9)-signalling in human fetal gonads alter sex-specific gonadal differentiation?SUMMARY ANSWERInhibition of FGFR signalling following SU5402 treatment impaired germ cell survival in both sexes and severely altered the developing somatic niche in testes, while stimulation of FGF9 signalling promoted Sertoli cell proliferation... Leggi di più
Pubblicato il 17-11-2019
Fonte: HUMAN REPRODUCTION - open access
AbstractSTUDY QUESTIONDoes experimental manipulation of fibroblast growth factor 9 (FGF9)-signalling in human fetal gonads alter sex-specific gonadal differentiation?SUMMARY ANSWERInhibition of FGFR signalling following SU5402 treatment impaired germ cell survival in both sexes and severely altered the developing somatic niche in testes, while stimulation of FGF9 signalling promoted Sertoli cell proliferation... Leggi di più
Pubblicato il 17-11-2019
Fonte: HUMAN REPRODUCTION - advance access
New England Journal of Medicine, Ahead of Print.... Leggi di più
Pubblicato il 16-11-2019
Fonte: NEW ENGLAND JOURNAL OF MEDICINE - current issue
By Patrizio Lancellotti
New England Journal of Medicine, Ahead of Print.... Leggi di più
Pubblicato il 16-11-2019
Fonte: NEW ENGLAND JOURNAL OF MEDICINE - current issue
By George D. Dangas
New England Journal of Medicine, Ahead of Print.... Leggi di più
Pubblicato il 16-11-2019
Fonte: NEW ENGLAND JOURNAL OF MEDICINE - current issue
By Ole De Backer
New England Journal of Medicine, Ahead of Print.... Leggi di più
Pubblicato il 16-11-2019
Fonte: NEW ENGLAND JOURNAL OF MEDICINE - current issue
By Duk-Hyun Kang
Medical Decision Making, Ahead of Print. Background. We aimed to validate the SURE test for use with parents in primary care. Methods. A secondary analysis of cluster randomized trial data was used to compare the SURE test (index, higher score = less conflict) to the Decisional Conflict Scale (DCS; reference,... Leggi di più
Pubblicato il 16-11-2019
Fonte: MEDICAL DECISION MAKING - recent articles
By Laura Boland
New England Journal of Medicine, Ahead of Print.... Leggi di più
Pubblicato il 16-11-2019
Fonte: NEW ENGLAND JOURNAL OF MEDICINE - current issue
By L. Kristin Newby
New England Journal of Medicine, Ahead of Print.... Leggi di più
Pubblicato il 16-11-2019
Fonte: NEW ENGLAND JOURNAL OF MEDICINE - current issue
By Jean-Claude Tardif
Purpose of review Incretin-based therapies mimic or augment the gut-hormone glucagon-like peptide (GLP)-1 and, due to their glucose-lowering potential and beneficial safety profile, as well as their cardiovascular safety and/or protection, are prescribed on a large scale to treat individuals with type 2 diabetes (T2D). However, whether the two drug-classes... Leggi di più
Pubblicato il 16-11-2019
Fonte: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION - most emailed articles
Purpose of review In recent years, doubt has been cast on the existence of contrast-induced acute kidney injury. The skepticism has stemmed from observational studies from large administrative healthcare databases. Although they correctly call that contrast-induced acute kidney injury is less common than previously thought, they cannot completely exclude selection... Leggi di più
Pubblicato il 16-11-2019
Fonte: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION - most emailed articles
Purpose of review In chronic kidney disease (CKD), disturbance of several metabolic regulatory mechanisms cause premature ageing, accelerated cardiovascular disease (CVD), and mortality. Single-target interventions have repeatedly failed to improve the prognosis for CKD patients. Epigenetic interventions have the potential to modulate several pathogenetic processes simultaneously. Alkaline phosphatase (ALP) is... Leggi di più
Pubblicato il 16-11-2019
Fonte: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION - most emailed articles
Il Riassunto delle Caratteristiche del Prodotto e il Foglio Illustrativo del medicinale IDRACAL (033486) sono stati modificati. Di seguito i link: Riassunto delle caratteristiche del prodotto Foglio illustrativo Attenzione! Si ricorda che le informazioni inerenti l’utilizzo di questo servizio sono pubblicate sul sito https://farmaci.agenziafarmaco.gov.it al link Condizioni di Utilizzo... Leggi di più
Pubblicato il 16-11-2019
Fonte: AIFA BANCA DATI FARMACI - aggiornamenti rcp e fi
AbstractSTUDY QUESTIONAre selective markers for the neuronal differentiation such as microtubule-associated protein 2 (MAP-2) and synaptophysin (SYP) as well as the nerve growth factor (NGF) expressed by fibroids, myometrium and eutopic endometrium?SUMMARY ANSWERNeuronal markers NGF, MAP-2 and SYP are highly expressed in fibroids compared with matched myometrium, and this neurogenic... Leggi di più
Pubblicato il 16-11-2019
Fonte: HUMAN REPRODUCTION - advance access
Purpose of the studyIron deficiency anaemia (IDA) is associated with increased morbidity and mortality in heart failure patients. The aim of our audit was to evaluate the current practice in diagnosis and assessment of IDA in patients admitted with heart failure.Study designWe conducted a retrospective audit of patients admitted to... Leggi di più
Pubblicato il 15-11-2019
Fonte: POSTGRADUATE MEDICAL JOURNAL - online first
By Simon, S., Ioannou, A., Deoraj, S., Metaxa, S., Mandal, A. K. J., Missouris, C. G.
The proliferation of medical misinformation on social media is a growing, global public health concern.1 The medical community is responding to this pervasive threat; earlier this year, the Chief Executive of the American Medical Association wrote to the leading technology companies calling for more action to ‘ensure that users have... Leggi di più
Pubblicato il 15-11-2019
Fonte: POSTGRADUATE MEDICAL JOURNAL - online first
By Trethewey, S. P.