News Chirurgia Toracica

Enterovirus D68 (EV-D68) causes respiratory illnesses such as pneumonia, and has been reported to cause acute flaccid myelitis. Enterovirus A71 (EV-A71) is known to cause cardiopulmonary failure due to brainstem encephalitis, but there have been few reports of these conditions being associated with EV-D68. Outbreaks of EV-D68 infection have occurred... Leggi di più
Pubblicato il 15-11-2019
Fonte: BMJ CASE REPORTS - recent articles
By Yogo, N., Imamura, T., Muto, Y., Hirai, K.
The Andrew Herxheimer memorial lecture at the 2019 Paris general assembly of the International Society of Drug Bulletins, delivered by Alan Cassels (Communications Director, Therapeutics Initiative, University of British Columbia) and Dee Mangin (Professor of Family Medicine at McMaster University), focused on the burden of overprescribing. Both speakers provided a... Leggi di più
Pubblicato il 14-11-2019
Fonte: DRUG AND THERAPEUTIC BULLETIN - online first
By Cave, J. A.
Long-term exposure to particulate matter 2.5 μm (PM2.5) air pollution is associated with an increased risk of lung cancer. However, the evidence is limited in low-income and middle-income countries. We estimated the association between the incidence of lung cancer and PM2.5 air pollution exposure in the Urban Employee Basic Medical... Leggi di più
Pubblicato il 14-11-2019
Fonte: THORAX - online first
By Zhang, Z., Zhu, D., Cui, B., Ding, R., Shi, X., He, P.
Background Despite advances in understanding the pathophysiology of acute respiratory distress syndrome, effective pharmacological interventions have proven elusive. We believe this is a consequence of existing preclinical models being designed primarily to explore biological pathways, rather than predict treatment effects. Here, we describe a mouse model in which both therapeutic... Leggi di più
Pubblicato il 14-11-2019
Fonte: THORAX - recent issues
By Oakley, C., Koh, M., Baldi, R., Soni, S., O'Dea, K., Takata, M., Wilson, M.
This month’s airwaves has a festive flavour... Incremental costs and Ebenezer Scrooge "If they would rather die, they had better do it, and decrease the surplus population." So said Ebenezer Scrooge in Charles Dickens’ "A Christmas Carol". His views may be a fictional reflection of those of the political economist... Leggi di più
Pubblicato il 14-11-2019
Fonte: THORAX - recent issues
By The Triumvirate
Background Perturbed iron homeostasis is a risk factor for tuberculosis (TB) progression and an indicator of TB treatment failure and mortality. Few studies have evaluated iron homeostasis as a TB diagnostic biomarker. Methods We recruited participants with TB, latent TB infection (LTBI), cured TB (RxTB), pneumonia (PN) and healthy controls... Leggi di più
Pubblicato il 14-11-2019
Fonte: THORAX - current issue only
By Dai, Y., Shan, W., Yang, Q., Guo, J., Zhai, R., Tang, X., Tang, L., Tan, Y., Cai, Y., Chen, X.
Treatment choices in COPD: guideline variance may be driven by patients’ phenotype There are an increasing number of maintenance therapies available for COPD. Adherence to Global initiative on chronic Obstructive Lung Disease (GOLD) guidelines by physicians has been shown to be poor but it is not clear if this variance... Leggi di più
Pubblicato il 14-11-2019
Fonte: THORAX - recent issues
By Walsh, C.
Retrospective analysis of the SUPERNOVA trial exploring the hypothesis that efficacy and safety of extracorporeal carbon dioxide removal (ECCO2R) to facilitate reduction of tidal volume (VT) to 4 mL/kg in patients with acute respiratory distress syndrome (ARDS) may differ between systems with lower (area of membrane length 0.59 m2; blood... Leggi di più
Pubblicato il 14-11-2019
Fonte: THORAX - current issue only
By Combes, A., Tonetti, T., Fanelli, V., Pham, T., Pesenti, A., Mancebo, J., Brodie, D., Ranieri, V. M.
Manchester’s ‘Lung Health Check’ pilot utilised mobile CT scanners in convenient retail locations to deliver lung cancer screening to socioeconomically disadvantaged communities. We assessed whether screening location was an important factor for those attending the service. Location was important for 74.7% (n=701/938) and 23% (n=216/938) reported being less likely to... Leggi di più
Pubblicato il 14-11-2019
Fonte: THORAX - current issue only
By Balata, H., Tonge, J., Barber, P. V., Colligan, D., Elton, P., Evison, M., Kirwan, M., Novasio, J., Sharman, A., Slevin, K., Taylor, S., Waplington, S., Booton, R., Crosbie, P. A.
Background It is unknown if adults born... Leggi di più
Pubblicato il 14-11-2019
Fonte: THORAX - recent issues
By Doyle, L. W., Irving, L., Haikerwal, A., Lee, K., Ranganathan, S., Cheong, J.
Background Despite advances in understanding the pathophysiology of acute respiratory distress syndrome, effective pharmacological interventions have proven elusive. We believe this is a consequence of existing preclinical models being designed primarily to explore biological pathways, rather than predict treatment effects. Here, we describe a mouse model in which both therapeutic... Leggi di più
Pubblicato il 14-11-2019
Fonte: THORAX - current issue only
By Oakley, C., Koh, M., Baldi, R., Soni, S., O'Dea, K., Takata, M., Wilson, M.
This month’s airwaves has a festive flavour... Incremental costs and Ebenezer Scrooge "If they would rather die, they had better do it, and decrease the surplus population." So said Ebenezer Scrooge in Charles Dickens’ "A Christmas Carol". His views may be a fictional reflection of those of the political economist... Leggi di più
Pubblicato il 14-11-2019
Fonte: THORAX - current issue only
By The Triumvirate
Serum IgA ≤70 mg/dL (low IgA) is associated with exacerbations of chronic obstructive pulmonary disease. The association of low IgA with longitudinal lung function is poorly defined. This study included 917 World Trade Center (WTC)-exposed firefighters with longitudinal spirometry measured between September 2001 and September 2018 and IgA measured between... Leggi di più
Pubblicato il 14-11-2019
Fonte: THORAX - recent issues
By Putman, B., Lahousse, L., Zeig-Owens, R., Singh, A., Hall, C. B., Liu, Y., Schwartz, T., Goldfarb, D., Webber, M. P., Prezant, D. J., Weiden, M. D.
Treatment choices in COPD: guideline variance may be driven by patients’ phenotype There are an increasing number of maintenance therapies available for COPD. Adherence to Global initiative on chronic Obstructive Lung Disease (GOLD) guidelines by physicians has been shown to be poor but it is not clear if this variance... Leggi di più
Pubblicato il 14-11-2019
Fonte: THORAX - current issue only
By Walsh, C.
Lung cancer and cardiovascular disease (CVD) are both leading causes of mortality and morbidity in the UK and worldwide.1 2 Every day in the UK, approximately 130 people learn that they have lung cancer, and nearly 100 die because of it.3 For CVD, the numbers are even greater; on average,... Leggi di più
Pubblicato il 14-11-2019
Fonte: THORAX - recent issues
By Fisk, M., Bolton, C. E.
Background It is unknown if adults born... Leggi di più
Pubblicato il 14-11-2019
Fonte: THORAX - current issue only
By Doyle, L. W., Irving, L., Haikerwal, A., Lee, K., Ranganathan, S., Cheong, J.