News Chirurgia Apparato Digerente

Enterovirus D68 (EV-D68) causes respiratory illnesses such as pneumonia, and has been reported to cause acute flaccid myelitis. Enterovirus A71 (EV-A71) is known to cause cardiopulmonary failure due to brainstem encephalitis, but there have been few reports of these conditions being associated with EV-D68. Outbreaks of EV-D68 infection have occurred... Leggi di più
Pubblicato il 15-11-2019
Fonte: BMJ CASE REPORTS - recent articles
By Yogo, N., Imamura, T., Muto, Y., Hirai, K.
The Andrew Herxheimer memorial lecture at the 2019 Paris general assembly of the International Society of Drug Bulletins, delivered by Alan Cassels (Communications Director, Therapeutics Initiative, University of British Columbia) and Dee Mangin (Professor of Family Medicine at McMaster University), focused on the burden of overprescribing. Both speakers provided a... Leggi di più
Pubblicato il 14-11-2019
Fonte: DRUG AND THERAPEUTIC BULLETIN - online first
By Cave, J. A.
Introduction Severe acute malnutrition (SAM) in children in many countries still carries unacceptably high mortality, especially when complicated by secondary infection or metabolic derangements. New therapies are urgently needed and we have identified mucosal healing in the intestine as a potential target for novel treatment approaches. Methods and analysis The... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Kelly, P., Bell, L., Amadi, B., Bwakura-Dangarembizi, M., VanBuskirk, K., Chandwe, K., Chipunza, M., Ngosa, D., Chulu, N., Hill, S., Murch, S., Playford, R., Prendergast, A.
Introduction Two of the most acute and feared complications in type 1 diabetes (T1D) are hypoglycaemia and severe hypoglycaemia (SH). While impaired awareness of hypoglycaemia (IAH) can lead to SH with cognitive and motivational barriers implicated, the available education does not integrate behavioural change techniques to address these. A novel... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Soukup, T., Hull, L., Smith, E. L., Healey, A., Bakolis, I., Amiel, S. A., Sevdalis, N., Group, P.
Objectives Premedication practices for neonatal tracheal intubations have not yet been described for neonatal transport teams. Our objective is to describe the use of sedation/analgesia (SA) for tracheal intubations and to assess its tolerance in neonates transported by medical transport teams in France. Setting This prospective observational study was part... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Carbajal, R., Lode, N., Ayachi, A., Chouakri, O., Henry-Larzul, V., Kessous, K., Normand, A., Courtois, E., Rousseau, J., Cimerman, P., Chabernaud, J.-L.
Background Septic shock is a life-threatening infection frequently responsible for hospital admissions or may be acquired as nosocomial infection in hospitalized patients with resultant significant morbidity and mortality . There is a dearth of data on a résumé and meta-analysis on the global epidemiology of this potentially deadly condition. Therefore,... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Tianyi, F. L., Tochie, J. N., Danwang, C., Mbonda, A., Temgoua, M. N., Mapoh, S. Y., Nkemngu, N. J., Tallah, E., Bigna, J. J.
Objective Low neighbourhood socioeconomic status (NSES) has been linked to a higher risk of overweight/obesity, irrespective of the individual’s own socioeconomic status. No meta-analysis study has been done on the association. Thus, this study was done to synthesise the existing evidence on the association of NSES with overweight, obesity and... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Mohammed, S. H., Habtewold, T. D., Birhanu, M. M., Sissay, T. A., Tegegne, B. S., Abuzerr, S., Esmaillzadeh, A.
Introduction Selective reporting bias, inconsistency in the chosen outcomes between trials and irrelevance of the chosen outcomes for women, limit the efficiency and value of research for prevention and treatment of gestational diabetes mellitus (GDM). One way to address these challenges is to develop core outcome sets (COSs). Methods and... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Egan, A. M., Dunne, F. P., Biesty, L. M., Bogdanet, D., Crowther, C., Dempsey, E., Thangaratinam, S., Devane, D., Fhelelboom, N., On behalf of the INSPIRED (INternational collaboration for Studies in PREgnacy and Diabetes) research group.
Introduction Depression represents a major public health concern for children and adolescents, and is thought to negatively impact subsequent educational attainment. However, the extent to which depression and educational attainment are directly associated, and whether other factors play a role, is uncertain. Therefore, we aim to systematically review the literature... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Wickersham, A., Epstein, S., Sugg, H. V. R., Stewart, R., Ford, T., Downs, J.
Objective This study aimed to explore the potential for the Waterlow score (WS) to be used as a predictor of 30-day mortality and length of hospital stay (LHS) in acutely admitted medical patients aged 65 years and older. Design Prospective observational cohort study. Setting UK District General Hospital. Subjects 834... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Wang, J. W., Smith, P., Sarker, S.-J., Elands, S., Oliveira, A., Barratt, C., Thorn, C., Holme, T., Lynch, M.
Introduction Rotavirus vaccines were introduced into the Australian National Immunisation Program in 2007. Despite this, Northern Territory Indigenous children continue to be hospitalised with rotavirus at a rate more than 20 times higher than non-Indigenous children in other Australian jurisdictions, with evidence of waning protection in the second year of... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Middleton, B. F., Jones, M. A., Waddington, C. S., Danchin, M., McCallum, C., Gallagher, S., Leach, A. J., Andrews, R., Kirkwood, C., Cunliffe, N., Carapetis, J., Marsh, J. A., Snelling, T.
Introduction Recurrent pregnancy loss (RPL) is defined as the spontaneous demise of two or more pregnancies before the fetus reaches viability. Despite investigation of multiple known maternal risk factors, in more than 50% of couples, this condition remains unexplained. Studies focusing on paternal factors in RPL are scarce, and therefore,... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By du Fosse, N., van der Hoorn, M.-L., Eikmans, M., Heidt, S., le Cessie, S., Mulders, A., van Lith, J., Lashley, E.
Introduction Recurrent pregnancy loss (RPL) is defined as the spontaneous demise of two or more pregnancies before the fetus reaches viability. Despite investigation of multiple known maternal risk factors, in more than 50% of couples, this condition remains unexplained. Studies focusing on paternal factors in RPL are scarce, and therefore,... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - protocol
By du Fosse, N., van der Hoorn, M.-L., Eikmans, M., Heidt, S., le Cessie, S., Mulders, A., van Lith, J., Lashley, E.
Objectives To explore participants’ views of Delphi surveys in core outcome set (COS) development. Study design and setting Patients and health professionals (n=24) from seven recently concluded COS studies that had involved a Delphi survey took part in semistructured qualitative interviews (telephone and email exchange). Interviews explored participants’ understanding of... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Biggane, A. M., Williamson, P. R., Ravaud, P., Young, B.
Recruiting participants into clinical trials is notoriously difficult and poses the greatest challenge when planning any investigative study. Poor recruitment may not only have financial ramifications owing to increased time and resources being spent but could adversely influence the clinical impact of a study if it becomes underpowered. Herein, we... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Ruban, A., Prechtl, C. G., Glaysher, M. A., Chhina, N., Al-Najim, W., Miras, A. D., Smith, C., P Goldstone, A., Patel, M., Moore, M., Ashrafian, H., Byrne, J. P., Teare, J. P.
Purpose The Danish Work Life Course Cohort (DaWCo) was initiated to study relations between working conditions, health and labour market affiliation using repeated measures of these factors throughout the working life, while accounting for health-differences pre-existing labour market entry. Participants The cohort encompasses all 15–30-year-old individuals residing in Denmark who... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Svane-Petersen, A. C., Framke, E., Sorensen, J. K., Rugulies, R., Madsen, I. E. H.