News Biochimica Chimica

Enterovirus D68 (EV-D68) causes respiratory illnesses such as pneumonia, and has been reported to cause acute flaccid myelitis. Enterovirus A71 (EV-A71) is known to cause cardiopulmonary failure due to brainstem encephalitis, but there have been few reports of these conditions being associated with EV-D68. Outbreaks of EV-D68 infection have occurred... Leggi di più
Pubblicato il 15-11-2019
Fonte: BMJ CASE REPORTS - recent articles
By Yogo, N., Imamura, T., Muto, Y., Hirai, K.
ObjectiveTo evaluate the cost-effectiveness of two technology assisted manual medication picking systems vs traditional manual picking.MethodsThis was a retrospective observational study comparing three outpatient pharmacies of a tertiary referral hospital in Singapore, where a light-emitting diode (LED-guided) manual picking system, an LED-guided manual picking plus lockable drawer (LED-LD) system, and... Leggi di più
Pubblicato il 14-11-2019
Fonte: EUROPEAN JOURNAL OF HOSPITAL PHARMACY - online first
By Teo, M. E. H., Chia, B. Y., Lee, Y. C., Tay, P. L. Y., Wong, J. A., Lee, S. B., Lim, M. M., Cheen, M. H. H.
The Andrew Herxheimer memorial lecture at the 2019 Paris general assembly of the International Society of Drug Bulletins, delivered by Alan Cassels (Communications Director, Therapeutics Initiative, University of British Columbia) and Dee Mangin (Professor of Family Medicine at McMaster University), focused on the burden of overprescribing. Both speakers provided a... Leggi di più
Pubblicato il 14-11-2019
Fonte: DRUG AND THERAPEUTIC BULLETIN - online first
By Cave, J. A.
Introduction Rotavirus vaccines were introduced into the Australian National Immunisation Program in 2007. Despite this, Northern Territory Indigenous children continue to be hospitalised with rotavirus at a rate more than 20 times higher than non-Indigenous children in other Australian jurisdictions, with evidence of waning protection in the second year of... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Middleton, B. F., Jones, M. A., Waddington, C. S., Danchin, M., McCallum, C., Gallagher, S., Leach, A. J., Andrews, R., Kirkwood, C., Cunliffe, N., Carapetis, J., Marsh, J. A., Snelling, T.
Introduction Recurrent pregnancy loss (RPL) is defined as the spontaneous demise of two or more pregnancies before the fetus reaches viability. Despite investigation of multiple known maternal risk factors, in more than 50% of couples, this condition remains unexplained. Studies focusing on paternal factors in RPL are scarce, and therefore,... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By du Fosse, N., van der Hoorn, M.-L., Eikmans, M., Heidt, S., le Cessie, S., Mulders, A., van Lith, J., Lashley, E.
Introduction Recurrent pregnancy loss (RPL) is defined as the spontaneous demise of two or more pregnancies before the fetus reaches viability. Despite investigation of multiple known maternal risk factors, in more than 50% of couples, this condition remains unexplained. Studies focusing on paternal factors in RPL are scarce, and therefore,... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - protocol
By du Fosse, N., van der Hoorn, M.-L., Eikmans, M., Heidt, S., le Cessie, S., Mulders, A., van Lith, J., Lashley, E.
Objectives To explore participants’ views of Delphi surveys in core outcome set (COS) development. Study design and setting Patients and health professionals (n=24) from seven recently concluded COS studies that had involved a Delphi survey took part in semistructured qualitative interviews (telephone and email exchange). Interviews explored participants’ understanding of... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Biggane, A. M., Williamson, P. R., Ravaud, P., Young, B.
Recruiting participants into clinical trials is notoriously difficult and poses the greatest challenge when planning any investigative study. Poor recruitment may not only have financial ramifications owing to increased time and resources being spent but could adversely influence the clinical impact of a study if it becomes underpowered. Herein, we... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Ruban, A., Prechtl, C. G., Glaysher, M. A., Chhina, N., Al-Najim, W., Miras, A. D., Smith, C., P Goldstone, A., Patel, M., Moore, M., Ashrafian, H., Byrne, J. P., Teare, J. P.
Purpose The Danish Work Life Course Cohort (DaWCo) was initiated to study relations between working conditions, health and labour market affiliation using repeated measures of these factors throughout the working life, while accounting for health-differences pre-existing labour market entry. Participants The cohort encompasses all 15–30-year-old individuals residing in Denmark who... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Svane-Petersen, A. C., Framke, E., Sorensen, J. K., Rugulies, R., Madsen, I. E. H.
Objectives We aimed to analyse the healthcare seeking behaviours (HSB) of populations with different migration status and examine the relationship between migration status and HSB. Design A secondary analysis of cross-sectional data of China Labor-force Dynamics Survey wave 2016, which was conducted by the Sun Yat-sen University every 2 years... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - recent issues
By Peng, B., Zhang, H., Shi, L., Ling, L.
Introduction The economic and health burden of sexually transmitted and genital infections (henceforth, STIs) in low-income and middle-income countries (LMICs) is substantial. Left untreated, STIs during pregnancy may result in several adverse pregnancy and birth outcomes. Timely diagnosis and treatment at point-of-care (POC) can potentially improve these outcomes. Despite the... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Saweri, O. P., Batura, N., Adawiyah, R. a., Causer, L., Pomat, W., Vallely, A., Wiseman, V.
Objectives Greenspace is one of the important factors that can promote an active lifestyle. Thus, greener surroundings may be a motivating factor for people with newly diagnosed diabetes to engage in more physical activity. Given that diagnosis of type 2 diabetes (T2D) may serve as a window opportunity for behavioural... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Chong, S., Mazumdar, S., Ding, D., Morgan, G., Comino, E. J., Bauman, A., Jalaludin, B.
Objectives The diagnosis and treatment of acute leukaemia (AL) affect physical, psychosocial and existential functioning. Long-lasting treatment periods with impaired immune system, hygienic and social restrictions challenge patient well-being and rehabilitation as compared with other individuals with cancer. This study elucidates how AL patients, treated with curative intent in an... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Jepsen, L. O., Friis, L. S., Hoybye, M. T., Marcher, C. W., Hansen, D. G.
Objective To identify the core components of successful early warning systems for detecting and initiating action in response to clinical deterioration in paediatric inpatients. Methods A hermeneutic systematic literature review informed by translational mobilisation theory and normalisation process theory was used to synthesise 82 studies of paediatric and adult early... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Jacob, N., Moriarty, Y., Lloyd, A., Mann, M., Tume, L. N., Sefton, G., Powell, C., Roland, D., Trubey, R., Hood, K., Allen, D.
Objective ‘Core information sets’ (CISs) represent baseline information, agreed by patients and professionals, to stimulate individualised patient-centred discussions. This study developed a CIS for use before colorectal cancer (CRC) surgery. Design Three phase consensus study: (1) Systematic literature reviews and patient interviews to identify potential information of importance to patients,... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By McNair, A. G. K., Whistance, R. N., Main, B., Forsythe, R., Macefield, R., Rees, J., Pullyblank, A., Avery, K., Brookes, S., Thomas, M. G., Sylvester, P. A., Russell, A., Oliver, A., Morton, D., Kennedy, R., Jayne, D., Huxtable, R., Hackett, R., Dutton, S., Coleman, M. G., Card, M., Brown, J., Blazeby, J.
Objectives We aimed to analyse the healthcare seeking behaviours (HSB) of populations with different migration status and examine the relationship between migration status and HSB. Design A secondary analysis of cross-sectional data of China Labor-force Dynamics Survey wave 2016, which was conducted by the Sun Yat-sen University every 2 years... Leggi di più
Pubblicato il 14-11-2019
Fonte: BMJ OPEN - current issue only
By Peng, B., Zhang, H., Shi, L., Ling, L.